Are there any known limitations with 7mm-08 Remington for large game?

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Effective Range for Whitetail When hunting whitetail deer, the effective range of the 7mm-08 Remington is typically considered to be 200-300 yards. However, this range can be extended to 400 yards or more with high-quality ammunition and a good shot placement. For optimal performance, look for bullets with a high ballistic coefficient (BC) and a muzzle velocity exceeding 2,700 feet per second.
Bullet Performance on Large Game While the 7mm-08 Remington can deliver enough energy to drop larger game, it may not be the most suitable choice for animals weighing over 500 pounds. For example, a 300-pound whitetail deer will typically require around 1,200-1,500 foot-pounds of kinetic energy to ensure a quick kill. In comparison, a 600-pound bear may require 2,000-2,500 foot-pounds of kinetic energy, which may be challenging for the 7mm-08 to achieve. To mitigate this, hunters can use larger bullets with a heavier mass, such as 140-grain or 150-grain options, or opt for a larger caliber altogether.
Shot Placement and Angles To compensate for the potential limitations of the 7mm-08 Remington, hunters must focus on precise shot placement and angles. This involves taking into account the animal’s weight, size, and body composition, as well as the range and trajectory of the bullet. Aiming for the heart-lung area is always a good rule of thumb, but this may require adjusting the point of aim based on the animal’s size and distance from the hunter. In some cases, a slightly higher or lower bullet trajectory may be necessary to ensure a clean kill.