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How to Identify CWD in Different Deer Species?

April 5, 2026

Quick Answer

Identifying Chronic Wasting Disease (CWD) in deer species involves observing symptoms such as unexplained weight loss, decreased coordination, and abnormal behavior, as well as post-mortem examination of lymph nodes and brain tissue for characteristic prion protein deposits.

Visual Inspection

When inspecting deer for CWD, look for animals that appear emaciated or have unexplained weight loss, even if they appear healthy otherwise. Monitor deer behavior, as CWD-infected animals often exhibit abnormal behavior such as lack of fear, increased aggression, or a decrease in social interaction. Also, note if deer are stumbling or showing signs of decreased coordination.

Laboratory Testing

To confirm CWD, collect lymph nodes, brain tissue, or rectal tissue samples from deceased deer and submit them to a laboratory for testing. It is recommended to use the immunohistochemistry (IHC) or enzyme-linked immunosorbent assay (ELISA) methods for detecting the CWD prion protein. These methods are accurate and reliable for detecting the disease.

Post-Mortem Examination

When performing a post-mortem examination of a deer suspected of having CWD, inspect the lymph nodes, particularly the retropharyngeal lymph nodes, for characteristic prion protein deposits. If the lymph nodes appear to have these deposits, it is likely that the deer was infected with CWD. It is also recommended to examine the brain tissue for the presence of prion protein deposits.

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