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Why choose .22-250 over .204 Ruger for coyotes?

May 8, 2026

Quick Answer

The .22-250 offers a slight edge over the .204 Ruger for coyote hunting due to its increased bullet weight and velocity, resulting in deeper penetration and more effective knockdown power at longer ranges.

Ballistic Advantage

When choosing between the .22-250 and .204 Ruger, consider the ballistic advantages of the .22-250. This cartridge typically launches a heavier bullet (around 55-60 grains) at a higher velocity (around 3,750-4,000 feet per second) compared to the .204 Ruger’s 32-40 grain bullet at 3,200-3,500 feet per second. This difference in weight and velocity translates to a flatter trajectory, allowing for more accurate shots at longer ranges, often beyond 300 yards.

Hunting Coyotes Effectively

For coyote hunting, effective knockdown power and penetration are crucial. The .22-250’s heavier bullet allows for deeper penetration, which is essential for quickly and humanely taking down coyotes, especially in areas with thick hide or muscle mass. Additionally, the .22-250’s higher velocity ensures that the bullet maintains its kinetic energy at longer ranges, increasing the chances of a clean kill. This is particularly important when hunting coyotes in open terrain where shots may be taken at longer distances.

Practical Considerations

In practical terms, the .22-250 is more versatile and suitable for a wider range of hunting applications, including hunting larger varmints like coyotes, prairie dogs, and jackrabbits. The cartridge’s slightly larger case capacity also allows for easier handloading and more flexibility in choosing the ideal bullet weight and powder combination. However, it’s worth noting that the .204 Ruger has its own advantages, particularly in terms of recoil and barrel life. Ultimately, the choice between the two cartridges depends on individual preference and specific hunting needs.

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